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Sitagliptin, branded as Januvia, is an oral DPP-4 inhibitor (dipeptidyl peptidase-4 inhibitor) used to treat type 2 diabetes mellitus. It works by inhibiting the enzyme DPP-4, which normally degrades the incretin hormones GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). Compare prices and print coupons for Sitagliptin (Januvia) and other drugs at CVS, Walgreens, and other pharmacies. Prices start at $44.18 Clayman Pharmacy provides North Americans with access to safe, affordable online prescription and refill processing. Just like your neighborhood drugstore. You can compare prices of Januvia among PharmacyChecker-verified international online pharmacies. Currently, 30 pills of Januvia 100 mg can cost patients over $540 at local U.S pharmacies. The same quantity of Januvia is as low as $34.99 at an international pharmacy. 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Compare prescription drug prices and find coupons at more than 70,000 US pharmacies. Save up to 80% instantly! Januvia (sitagliptin) is a prescription-only diabetes medication in the form of tablets that helps control blood sugar levels in people with type 2 diabetes mellitus. Januvia works by regulating insulin levels after eating or drinking. In some cases, Januvia is used in conjunction with other type 2 diabetes treatments to reduce diabetes side effects and the risk of further associated health … This guide walks you through the most affordable and effective diabetes medications available in 2025, how to discuss cost-saving alternatives with your provider, and where to buy medications for less—including from Canada. Januvia is a brand-name medication that's prescribed to help manage type 2 diabetes. Januvia is not available in a generic version. The cost of Januvia with or without insurance can depend on several factors. It might be lowered by using a coupon. 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