Transfer your prescription for Ondansetron (Generic for Zofran, Disintegrating Oral Tablet) on Amazon Pharmacy. FREE SHIPPING for Prime members. Ondansetron (Zofran) is prescription-only, but OTC alternatives like meclizine, Dramamine, and ginger can help with nausea. Learn your options. ONDANSETRON (on DAN se tron) prevents nausea and vomiting from chemotherapy, radiation, or surgery. It works by blocking substances in the body that may cause nausea or vomiting. It belongs to a group of medications called antiemetics. Zofran (ondansetron) – A prescription oral tablet used to prevent and treat nausea and vomiting, often recommended for stomach flu, migraines, or after medical treatments like chemotherapy. Prevent nausea and vomiting with affordable ondansetron (Zofran®). Get a prescription online from U.S. licensed physicians for $25 per treatment after a $39 no-wait consult. Zofran (ondansetron) is an antiemetic prescription that helps manage nausea and vomiting. 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