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It contains two active ingredients, lamivudine and zidovudine, which both belong to a class of drugs known as nucleoside reverse transcriptase inhibitors. Lamivudine-Zidovudine is a generic prescription combination drug used to control the underlying viral infection that causes HIV/AIDS. Lamivudine-Zidovudine are the active ingredients in brand-name Combivir. Lamivudine-Zidovudine costs $875.67 at full price. A SingleCare Lamivudine-Zidovudine coupon reduces that price to $35.99. Free tool to compare prescription prices across pharmacies and discount programs. No account or insurance needed. Prices vary by pharmacy. Lamivudine Generic Epivir and Epivir Hbv Drug Info Side Effects Dosage Medicare Specialty drug How to get this medication Lamivudine is a specialty medication, which can cost more than standard prescriptions and involve a few extra steps. We'll help you understand what to expect. Combivir combines lamivudine 150 mg and zidovudine 300 mg for HIV therapy. 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