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Common side effects of Avalide include: dizziness, lightheadedness, drowsiness, headache, blurred vision, stomach upset or pain, heartburn, muscle pain … Avalide (hydrochlorothiazide and irbesartan) is used to treat high blood pressure (hypertension). Includes Avalide side effects, interactions and indications. Irbesartan-Hydrochlorothiazide or Avalide Savings, Coupons and Information. | IRBESARTAN; HYDROCHLOROTHIAZIDE (ir be SAR tan; hye dro klor oh THYE a zide) treats high blood pressure. It relaxes your blood vessels and helps your kidneys remove more fluid through the urine, which lowers blood pressure. Get the best price on Avalide at pharmacies near you with SingleCare. Save up to 80% with our Avalide coupons – with or without insurance! Irbesartan/hydrochlorothiazide is commonly used to lower high blood pressure (hypertension). Compare Avalide prices and find coupons that could save you up to 80% instantly at pharmacies near you such as CVS, Walgreens, Walmart, and many more. 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